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UBMD Physicians' Group
Manoj                          Mammen

Manoj J. Mammen MD

UBMD Medicine


Bioinformatics; Critical Care Medicine; Internal Medicine; Pulmonary; Pulmonary & Critical Care Medicine; Pulmonary Disease



Professional Summary:

I am engaged in clinical, teaching and research responsibilities related to the evaluation and treatment of patients with pulmonary disease or patients who are critically ill. My inpatient practice is primarily located at the medical intensive care unit (MICU) at the Buffalo General Medical Center (BGMC). The MICU provides ongoing medical care to patients who are critically ill and require significant life support therapies to sustain life or vital bodily functioning.

I also evaluate patients with pulmonary disorders including shortness of breath, lung masses, abnormal chest imaging, abnormal pulmonary function tests, chronic obstructive pulmonary disease (COPD), asthma, interstitial lung disease, pulmonary hypertension and lung cancer, at the lung and heart outpatient clinic located in BGMC. The pulmonary team to which I belong also provides inpatient pulmonary consultation at both BGMC and Roswell Park Cancer Institute.

I am specifically interested in asthma, COPD and lung cancer. I am investigating the pathophysiology of lung inflammation.

Recently I am engaged in the study of the human airways microbiome and metagenome. The human microbiome is the the collection of all the microbial organisms in a human body, and the corresponding metagenome is the collection of the genes, and gene products of the microbes. Due the potential impact of the microbiome on human health and disease, I am interested in studying the putative effects the interaction with human hosts, specifically innate immunity interaction with the metagenome in lung disease.

Additionally, I collaborate with the Division of Allergy and Immunology and the Institute of Laser, Photonics and Biophotonics to elucidate immune cell function in airway diseases such as asthma and COPD. Our research focuses on the development of therapeutics aimed at novel targets identified as important in the molecular basis of pulmonary disease; efficacious laboratory results will generate more effective treatment plans for patients.

I am actively involved in teaching medical students, residents and fellows about the appropriate care of the critically ill patient, as these trainees rotate in the MICU.


Bioinformatics, Critical Care Medicine, Internal Medicine, Pulmonary, Pulmonary & Critical Care Medicine, Pulmonary Disease

Additional Languages:

Basic Spanish

Physician Gender:


Location and Insurance

Hospital Locations (for inpatients only):
  • Buffalo General Medical Center
Insurance Accepted:
  • Aetna U.S. Healthcare
  • Better Health Plan, Inc. (HMO)
  • Blue Cross & Blue Shield of WNY Inc
  • CIGNA HealthCare
  • Community Blue (HMO)
  • Community Blue Advantage
  • Empire
  • Fidelis
  • GHI
  • Independent Health Association (HMO)
  • Magnacare
  • Medicaid
  • Medicare
  • NYS Medicaid
  • United Healthcare
  • Univera Health Care (HMO)


Board Certifications:
  • Board Certification, American Board of Internal Medicine-Critical Care Medicine
  • Board Certification, American Board of Internal Medicine-Internal Medicine
  • Board Certification, American Board of Internal Medicine-Pulmonary Disease
Education and Training:
  • MS, Genetics, Genomics and Bioinformatics, University at Buffalo (2016)
  • Fellowship, Pulmonary & Critical Care Medicine, Baylor College of Medicine (2010)
  • Residency, Internal Medicine, Baylor College of Medicine (2007)
  • MD, Medicine, Rutgers New Jersey Medical School (2004)
  • BA, Molecular Biology & Biochemistry/Computer Science, Rutgers University (1999)
Awards and Honors:
  • Empire Clinical Research Investigator Program Fellow (2014)
  • Gold Humanism Honor Society (2004)
  • Rutgers Presidential Scholarship (1995)
  • Robert C. Byrd Federal Scholarship (1995)


Research Profile:

This UBMD clinician teaches at the University at Buffalo's School of Medicine and Biomedical Sciences. Learn more about this clinician’s research and teaching activities. View credentials, publications, professional involvement and more.