James Fallavollita
Medicine
Veterans Hospital
3495 Bailey Ave
Buffalo, NY 14215
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OFFICE LOCATIONS
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UBMD Internal Medicine 3980 Sheridan Drive 6th Floor Amherst, NY 14226 Phone: 716-882-6544 Fax: 716-882-6833 Contact: Jill Balbuzoski Hours: 8am-4:30pm View Map |
Insurance Accepted Aetna U.S. Healthcare Blue Cross & Blue Shield of WNY Inc CIGNA HealthCare Community Blue (HMO) Empire Fidelis GHI Independent Health Association (HMO) Medicare NYS Medicaid North American Administrators Nova Preferred Care Railroad Medicare Univera Health Care (HMO) |
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VA Medical Center 3495 Bailey Ave Buffalo, NY 14215 Phone: 862-8641 View Map |
Insurance Accepted Aetna U.S. Healthcare Better Health Plan, Inc. (HMO) Community Blue (HMO) Empire Fidelis Independent Health Association (HMO) United Healthcare Univera Health Care (HMO) |
DESCRIPTION OF INTERESTS
| -My research interests primarily involve the myocardial responses and adaptations to chronic ischemia. This research includes both basic and clinical aspects, with the majority of my efforts involved in clinical projects at this time. Our laboratory has developed a porcine model of chronic hibernating myocardium and our initial work has focused on flow and function with particular attention to inotropic and vasodilatory reserve. In addition to standard physiological measurements and correlations, we are using imaging and telemetry to understand the metabolic, molecular, and electrophysiological adaptations to ischemia and to test various therapies. My clinical research interests parallel this basic line of investigation. I am interested in using imaging and electrocardiographic monitoring to identify patients with left ventricular dysfunction who are most liekly to benefit from advanced device therapies. |
SPECIALTIES
Cardiology
PUBLICATIONS
| Banas, M.D. Young, H. Fallavollita, J.A. Canty, J.M., Jr.; Persistent reductions in flow and function after revascularization of swine with hibernating myocardium.; Journal of the American College of Cardiology; 2006; |
| Suzuki, G. Lee, T.C. Fallavollita, J.A. Canty, J.M., Jr.; Adenoviral gene transfer of FGF-5 to hibernating myocardium improves function and stimulates myocytes to hypertrophy and reenter the cell cycle.; Circulation Research; 2005; 96; 767-775 |
| Gangasani, A. Sidhu, S. Fallavollita, J.A. Korotchkina, L. G. Suzuki, G. Patel, M.S. Canty, J.M., Jr.; Cardiac pyruvate dehydrogenase complex (PDC) deficiency in mice leads to myocardial hypertrophy and cardiomyopathy.; Circulation; 2005; 112(II); II-21-II-22 |
| Luisi AJ Fallavollita, J.A. Luisi, A.J. Valverde, A.M. Michalek, S.M. Heavey, B.M. Canty, J.M.; Electrocardiographic risk stratification of sudden cardiac death.; J Electrocardiol; 2005; 35(4S); 140-140 |
| Canty, J. M. Fallavollita, J. A.; Hibernating myocardium; J Nucl Cardiol; 2005; 12(1); 104-119 |
| Fallavollita, J.A. Riegel, B.J. Suzuki, G. Valeti, U. Canty, J.M., Jr.; Mechanism of sudden cardiac death in pigs with viable chronically dysfunctional myocardium and ischemic cardiomyopathy; American Journal of Physiology - Heart & Circulatory Physiology; 2005; 289; H2688-H2696 |
| Luisi AJ Canty, J.M., Jr. deKemp, R.A. Haka, M.S. Toorongian, S.A. Fallavollita, J.A.; Patients with ischemic cardiomyopathy eligible for ICD therapy demonstrate extensive sympathetic denervation out of proportion to previous infarction.; Circulation; 2005; 112; 472-472 |
| Canty JM, Suzuki G, Banas MD, Verheyen F, Borgers M, Fallavollita JA; Hibernating Myocardium. Chronically Adapted to Ischemia but Vulnerable to Sudden Death.; Circ Res; 2004 Mar; |
| Thijssen VL, Borgers M, Lenders MH, Ramaekers FC, Suzuki G, Palka B, Fallavollita JA, Thomas SA, Canty JM Jr; Temporal and Spatial Variations in Structural Protein Expression During the Progression From Stunned to Hibernating Myocardium; Circulation; 2004; 110(21); 2213-2221 |
| Canty JM, Fallavollita JA; Sympathetic nerves and myocyte necrosis: more than meets the eye.; Circ Res; 2003 Oct; 93(9); 796-798 |
| Fallavollita JA, Malm BJ, Canty JM; Hibernating myocardium retains metabolic and contractile reserve despite regional reductions in flow, function, and oxygen consumption at rest.; Circ Res; 2003 Jan; 92(1); 48-55 |
| Malm BJ, Suzuki G, Canty JM, Fallavollita JA; Variability of contractile reserve in hibernating myocardium: dependence on the method of inotropic stimulation.; Cardiovasc Res; 2002 Dec; 56(3); 422-432 |
| Thomas SA, Fallavollita JA, Suzuki G, Borgers M, Canty JM; Dissociation of regional adaptations to ischemia and global myolysis in an accelerated Swine model of chronic hibernating myocardium.; Circ Res; 2002 Nov; 91(10); 970-977 |
| Luisi AJ, Fallavollita JA, Suzuki G, Canty JM; Spatial inhomogeneity of sympathetic nerve function in hibernating myocardium.; Circulation; 2002 Aug; 106(7); 779-781 |
| Fallavollita JA, Logue M, Canty JM; Coronary patency and its relation to contractile reserve in hibernating myocardium.; Cardiovasc Res; 2002 Jul; 55(1); 131-140 |
| Fallavollita JA, Canty JM; Ischemic cardiomyopathy in pigs with two-vessel occlusion and viable, chronically dysfunctional myocardium.; Am J Physiol Heart Circ Physiol; 2002 Apr; 282(4); 1370-1379 |
| Fallavollita JA, Lim H, Canty JM; Myocyte apoptosis and reduced SR gene expression precede the transition from chronically stunned to hibernating myocardium.; J Mol Cell Cardiol; 2001 Nov; 33(11); 1937-1944 |
| Canty JM, Fallavollita JA; Lessons from experimental models of hibernating myocardium.; Coron Artery Dis; 2001 Aug; 12(5); 371-380 |
| Fallavollita JA, Logue M, Canty JM; Stability of hibernating myocardium in pigs with a chronic left anterior descending coronary artery stenosis: absence of progressive fibrosis in the setting of stable reductions in flow, function and coronary flow reserve.; J Am Coll Cardiol; 2001 Jun; 37(7); 1989-1995 |
| Feng J, Schaus BJ, Fallavollita JA, Lee TC, Canty JM; Preload induces troponin I degradation independently of myocardial ischemia.; Circulation; 2001 Apr; 103(16); 2035-2037 |
| Feng J, Schaus BJ, Fallavollita JA, Lee TC & Canty JM Jr; Preload induces troponin degradation independently of myocardial ischemia; Circ. Res.; 2001 Jan; 103; 2035-2037 |
| Fallavollita JA, Trojan C, Canty JM; Transmural distribution of FDG uptake in stunned myocardium.; Am J Physiol Heart Circ Physiol; 2000 Jul; 279(1); 102-109 |
| Canty JM, Fallavollita JA; Chronic hibernation and chronic stunning: a continuum.; J Nucl Cardiol; 2000; 7(5); 509-527 |
| Lim H, Fallavollita JA, Hard R, Kerr CW, Canty JM; Profound apoptosis-mediated regional myocyte loss and compensatory hypertrophy in pigs with hibernating myocardium.; Circulation; 1999 Dec; 100(23); 2380-2386 |
| Fallavollita JA, Jacob S, Young RF, Canty JM; Regional alterations in SR Ca(2+)-ATPase, phospholamban, and HSP-70 expression in chronic hibernating myocardium.; Am J Physiol; 1999 Oct; 277(4 Pt); 1418-1428 |
| Thomas SA, Fallavollita JA, Lee TC, Feng J, Canty JM; Absence of troponin I degradation or altered sarcoplasmic reticulum uptake protein expression after reversible ischemia in swine.; Circ Res; 1999 Sep; 85(5); 446-456 |
| Canty JM, Fallavollita JA; Resting myocardial flow in hibernating myocardium: validating animal models of human pathophysiology.; Am J Physiol; 1999 Jul; 277(1 Pt); 417-422 |
| Fallavollita JA, Canty JM; Differential 18F-2-deoxyglucose uptake in viable dysfunctional myocardium with normal resting perfusion: evidence for chronic stunning in pigs.; Circulation; 1999 Jun; 99(21); 2798-2805 |
| Fallavollita JA, Perry BJ, Canty JM; 18F-2-deoxyglucose deposition and regional flow in pigs with chronically dysfunctional myocardium. Evidence for transmural variations in chronic hibernating myocardium.; Circulation; 1997 Apr; 95(7); 1900-1909 |
| Fallavollita JA, Kumar K, Brody AS, Bunnell IL, Canty JM; Detection of coronary artery calcium to differentiate patients with early coronary atherosclerosis from luminally normal arteries.; Am J Cardiol; 1996 Dec; 78(11); 1281-1284 |
| Canty JM, Fallavollita JA; Hibernating myocardium represents a primary downregulation of regional myocardial oxygen consumption distal to a critical coronary stenosis.; Basic Res Cardiol; 1995 Jan; 90(1); 5-8 |
| Fallavollita JA, Brody AS, Bunnell IL, Kumar K, Canty JM; Fast computed tomography detection of coronary calcification in the diagnosis of coronary artery disease. Comparison with angiography in patients < 50 years old.; Circulation; 1994 Jan; 89(1); 285-290 |