Mario Santilli

Mario D. Santilli

Mario D. Santilli MD

UBMD Orthopaedics & Sports Medicine


Adult Hip & Knee Arthroplasty; Arthroplasty - Hip & Knee; Knee Surgery; Lower Extremity Joint Replacement & Reconstruction; Orthopaedic Surgery; Reconstruction


Professional Summary:

As an orthopedic surgeon my clinical practice focuses on adult hip and knee reconstructive surgery. Practicing in Buffalo for the last thirty-two years has equipped me with a wealth of experience and expertise in caring for patients from diverse cultures from around the globe.

I currently see patients out of the UBMD Orthopaedics & Sports Medicine office in Amherst, New York, but my primary hospital is the Buffalo General Medical Center. Here I work with orthopedic residents and a dedicated team of orthopaedic nurses, technologists, therapists and social services professionals.

I enjoy the teaching component of my faculty role, which includes mentoring of orthopedic residents as well as medical and nursing students. Together with other medical professionals, we promote research projects aimed at improving the care we provide for our patients. I feel fortunate to be an assistant clinical professor for the Department of Orthopaedics, and look forward to many more opportunities to serve the orthopaedic needs of Western New York.


Adult Hip & Knee Arthroplasty, Arthroplasty - Hip & Knee, Knee Surgery, Lower Extremity Joint Replacement & Reconstruction, Orthopaedic Surgery, Reconstruction

Physician Gender:


Board Certifications:

  • Board Certification, American Board of Orthopaedic Surgeons

Education and Training:

  • Residency, Department of Orthopaedics, State University of New York at Buffalo (1983)
  • General Surgery, Millard Fillmore Hospital (1979)
  • MD, State University of New York at Buffalo, School of Medicine & Biomedical Sciences (1978)
  • BA, Canisius College, Cum Laude (1974)

Awards and Honors:

  • President, Alpha Theta Chapter, Beta Beta, Biological Honor Society (1974)

Research Profile:

This UBMD physician is also a member of the Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo, teaching the next generation of doctors and researching to advance care in WNY and beyond. Learn more about this physician's research and teaching activities, as well as view credentials, publications, professional involvement and more below.

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