University at Buffalo - The State University of New York
Skip to Content
UBMD Physicians' Group
Mark                           Hicar

Mark D. Hicar MD, PhD

UBMD Pediatrics


Pediatric Infectious Diseases; Pediatrics



Professional Summary:

My lab currently focuses B cell responses during inflammation with current main projects focusing on HIV and Kawasaki disease.

Currently, the HIV field is in desperate need for greater knowledge regarding the mechanisms involved in induction of neutralizing antibodies and mucosal immune responses against HIV. I have characterized a collection of human antibodies that target structural epitopes on the Envelope protein of HIV. Current work is being pursued to define the targets of these antibodies and to assess if they can recognize cutting edge HIV vaccine candidates. Designing improved immunogens that elicit enhanced antibody activity from vaccination is the overall goal of my HIV research.

Kawasaki Disease (KD) is an inflammatory disorder of children that can lead to dire consequences. KD is the leading cause of acquired heart disease in children and primarily affects children under 5 years of age. However, the cause remains unknown. Some groups have shown indications that B cell responses target a specific entity. My work focuses on characterizing how KD presents in Western New York and explores a role for specific B cell responses in the pathogenesis of this mysterious disease.

In my career I hope to become an accomplished physician-scientist who significantly impacts both the fields of lymphocyte development and HIV infection. Mucosal immune responses are of particular interest since they are so vital in the first line of defense in HIV and most other viral infections.


Pediatric Infectious Diseases, Pediatrics

Patients Treated:

Children, Adolescents

Physician Gender:


Location and Insurance

UBMD Pediatrics Outpatient Center
1001 Main Street
4th Floor
Buffalo, NY 14203
Office Hours: Tuesday: 8:00 am-12:00 pm; Wednesday: 1:00 pm-5:00 pm
Phone: (716) 323-0150
Fax: (716) 323-0296
Accepting new patients

Insurance Accepted:
  • Aetna U.S. Healthcare
  • Blue Cross & Blue Shield of WNY Inc
  • CIGNA HealthCare
  • Community Blue (HMO)
  • Community Blue Advantage
  • Coventry
  • Empire
  • Fidelis
  • Independent Health Association (HMO)
  • Independent Health Medisource
  • Lifetime Benefit Solutions / RMSCO
  • Magnacare
  • Medicaid
  • Medicare
  • MVP Healthcare
  • Nofault
  • North American Administrators
  • Nova
  • Preferred Care
  • Railroad Medicare
  • Tricare
  • TriCare/Champus
  • United Healthcare
  • Univera Health Care (HMO)
  • Veterans Administration
  • WellCare
  • Workers Comp
  • YourCare


Board Certifications:
  • Board Certification, American Board of Pediatrics
  • Board Certification, American Board of Pediatrics, Sub-board in Pediatric Infectious Diseases
Education and Training:
  • Fellowship, Pediatric Infectious Diseases, Vanderbilt University School of Medicine (2009)
  • Residency, Pediatrics, Vanderbilt University School of Medicine (2005)
  • Internship, Pediatrics, Vanderbilt University School of Medicine (2003)
  • MD, Medicine, Ohio State University College of Medicine (2002)
  • PhD, Molecular Virology, Immunology and Medical Genetics, Ohio State University College of Medicine (2002)
  • BA, Biology, University of Chicago (1993)
Awards and Honors:
  • Human Antibodies International Journal: 14th Annual International Conference on Human Antibodies and Hybridomas (Invited Speaker) (2008)
  • Pediatric Academic Societies: Travel Award (2008)
  • Keystone Conference: HIV Pathogenesis Travel Award (2008)
  • American Association of Immunologists: Travel Award (2007)
  • Vanderbilt Pediatric House Staff: David Karzon Research Award (2005)
  • Ohio State University: Landacre Day - 1st Place Poster Presentation (1998)
  • Ohio State University: Medical Microbiology and Immunology Teaching Assistantship (1997)
  • Ohio State University: Molecular Life Sciences Fellowship (1996)
  • Ohio State University: Roessler Fellowship (1996)
  • Phi Beta Kappa Honor Society (1989)
  • University of Chicago: National Merit Scholar (1989)
  • Infectious Diseases Society of America (IDSA), ERF/NFID: Wyeth Young Investigator Award in Vaccine Development (2009-2011)
  • Pediatric Infectious Diseases Society and St. Jude Fellowship in Basic Research (2006-2009)
  • National Institutes of Health: Loan Repayment Award (2006-2012)
  • Ohio State University: Medical Scientist Fellowship (1998-2002)


Research Profile:

This UBMD clinician teaches at the University at Buffalo's School of Medicine and Biomedical Sciences. Learn more about this clinician’s research and teaching activities. View credentials, publications, professional involvement and more.