Sangita Patel

Sangita P. Patel

Sangita P. Patel MD, PhD

UBMD Ophthalmology at the Ross Eye Institute


Cornea & External Disease; Ophthalmology; Vision science

Accepting new patients

Professional Summary:

As a specialist in cornea and external diseases of the eye, I treat a wide range of eye problems and perform a variety of surgical procedures including corneal transplantation, cataract surgery, conjunctival tumor surgery, and transplantation of the artificial cornea when standard corneal transplantation has failed.

One of the most common reasons for corneal transplantation is corneal edema. Edema of the cornea develops from loss of corneal endothelial cells and causes irreversible vision loss in thousands of people yearly. Beyond surgical transplantation of the endothelial cell layer with human donor corneal tissue, no vision-restoring treatments are available. My research investigates the physiology regulating corneal hydration to advance future treatments for these patients. There are two main projects in my lab. The first looks at characterizing changes occurring in endothelial cell monolayer intercellular junctions and passive paracellular transport properties at low and high cell densities. Clinically, patients do not experience deterioration in vision or corneal edema until very low densities. The molecular basis for this observation is unknown. This project investigates changes in the apical junctional complex and monolayer permeability of the endothelium. The second project examines the mechanisms and regulation of active water transport out of the cornea. Using Ussing chamber physiology techniques, my lab is isolating the contributions and regulation of various ionic currents across the corneal endothelium with a focus on the contributions of potassium channels, bicarbonate and carbonic anhydrase inhibitors.


Cornea & External Disease, Ophthalmology, Vision science

Patients Treated:

Adults, Seniors/Elderly

Physician Gender:



UBMD Ophthalmology: Ross Eye Institute
Ross Eye Institute
1176 Main Street
Buffalo, NY 14209
Office Hours: Monday 8am-11am; Wednesday 12:30pm-3:30pm
Phone: (716) 881-7900
Accepting new patients

Insurance Accepted:

  • Aetna U.S. Healthcare
  • Blue Cross & Blue Shield of WNY Inc
  • CIGNA HealthCare
  • Fidelis
  • Independent Health Association (HMO)
  • Medicaid
  • Medicare
  • Nofault
  • Nova
  • United Healthcare
  • Veterans Administration
  • Workers Comp

Education and Training:

  • Fellowship, Cornea, Refractive Surgery and External Diseases, Massachusetts Eye and Ear Infirmary, Harvard Medical School (2009)
  • Residency, Ophthalmology, Mayo Clinic College of Medicine (2008)
  • Internship, Internal Medicine, Winthrop University Hospital (2005)
  • MD, Physiology (Ph.D.), University at Buffalo, School of Medicine and Biomedical Sciences, Cum Laude (2004)
  • BA, Biology, New York University, Magna Cum Laude (1997)

Awards and Honors:

  • John Dyer Award (2008)
  • Heed Ophthalmic Foundation (2007)
  • E.J. Weisenheimer Award (2004)
  • Alpha Omega Alpha (2003)
  • Gilbert D. Moore Fellowship (1999)
  • Dean's Letter of Commendation (1999)
  • New York University Honors Scholar (1996)
  • Phi Beta Kappa (1996)
  • Dean's Honor List (1996)
  • Trustee Scholarship (1996)

Research Profile:

This UBMD physician is also a member of the Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo, teaching the next generation of doctors and researching to advance care in WNY and beyond. Learn more about this physician’s research and teaching activities, as well as view credentials, publications, professional involvement and more below.

UBMD News: